The Australian Children's Brain Cancer Conference 2024
- 7-8 March 2024
- Brisbane Convention & Exhibition Centre
Some of the world brightest medical minds came together in the final weekend of March to tackle paediatric brain cancer, sharing insights and research findings to bolster the fight against the insidious childhood disease.
View 2024 Program
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08:00 |
Registration Open - Tea and coffee available |
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09:00 |
Acknowledgement of Country Conference Opening |
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09:15-10:30 |
Plenary Session: Translational Molecular Pathology |
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Session Chair: Prof Brandon Wainwright Molecular characterization and clinical implications for paediatric glioma Dr Cynthia Hawkins A Systems Biology Approach to Mapping Genetic Dependencies in Paediatric Brain Cancer Prof Ron Firestein |
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10:30-11:00 |
Morning tea with poster viewing |
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11:00-12:20 |
Selected Abstracts |
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Session Chair: Ms Anja Kordowski
Targeting Post-Translational Protein Modification to Halt Diffuse Midline Glioma Tumorgenicity Dr Benjamin Rayner Novel Formulation to Target MYCN expression and Copper Level in DIPG and Overcome Multidrug Resistance Dr Riccardo Cazzoli DRD2 antagonism induces immune-tumour surveillance, warming the tumor immune microenvironment of diffuse midline glioma models Miss Mika Persson Rational combination targeting of therapeutic dependencies in Diffuse Midline Glioma Dr Ryan Duchatel |
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12:20-13:30 |
Lunch |
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13:30-15:00 |
Plenary Session: Epigenetics |
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Session Chair: Prof Raelene Endersby Human prefrontal cortex gene regulatory dynamics from gestation to adulthood at single-cell resolution
Prof Ryan Lister Speaker involvement made possible thanks to the support from 
Exploring the boundaries of nuclear reprogramming Prof Jose Polo RNA-mediated regulation of PRC2 – lessons from a complex story Dr Qi Zhang |
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15:00-15:30 |
Afternoon tea with poster viewing |
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15:30-17:00 |
Plenary Session: Clinical Implementation |
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Session Chair: Prof Greig du Zubicaray
The First Year of Accredited Methylation Array Profiling in Australia Dr Christine White The utility of cancer genomic testing in paediatric cancer Assoc Prof Aideen McInerney-Leo Pediatric Low Grade Glioma Survivors’ Need for Survivorship Care: Piloting ‘Engage’ a Multidisciplinary, E-Health Intervention. Dr Jordana McLoone The program session made possible thanks to the support from  |
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17:00 |
Poster session |
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18:00 |
Close |
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19:00-22:00 |
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08:00 |
Registration Open - Tea and coffee available |
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09:00 |
Opening |
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09:15-10:30 |
Plenary Session: Gliomagenesis and Preclinical Models |
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Session Chair: Prof Bryan Day
Injury reprogramming at the origin of glioma Dr Peter Dirks Emulating natural tissue barriers in the laboratory to improve preclinical cancer models Prof Geraldine O'Neill |
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10:30-11:00 |
Morning tea with poster viewing |
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11:00-12:20 |
Selected Abstracts
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Session Chair: Dr Marija Kiska
Addressing the blood-brain barrier challenge in Diffuse Midline Glioma Dr Maria Tsoli ATR Inhibitor AZD6738 Enhances the Efficacy of Chemotherapy and Radiation in Preclinical Models of Medulloblastoma Dr Meegan Howlett CD63 is a tumour associated antigen for DMG and can be targeted with novel CD63 CAR T cells Dr Alexander Davenport Spatial Transcriptomic Sequencing of a DIPG Patient Tumour Resource Ms Anja Kordowski |
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12:20-13:30 |
Lunch |
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13:30-15:00 |
Plenary Session: Breakthroughs and Bioinformatics |
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Session Chair: Prof Misty Jenkins
Changing the paradigm for childhood brain cancer Prof David Ziegler Mapping differential responses to drug using spatial multiomics Dr Quan Nguyen Computational immunogenomic approaches to predict neoantigens treatment response Dr Venkat Addala |
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15:00-15:30 |
Afternoon tea with poster viewing |
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15:30-16:45 |
Plenary Session: Innovative Therapeutics |
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Session Chair: Dr Tim Hassall
FLASH Radiotherapy: A Synergy of Physics, Biology and Medicine Dr Anthony Mascia Tackling Childhood Brain Cancer on a Tiny Scale Prof Maria Kavallaris |
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16:45-17:15 |
Awards and Closing |
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17:30-19:30 |
Conference Networking Function, Brisbane Convention & Exhibition Centre View information |
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Children's Brain Cancer Conference 2023
- 23-24 March 2023
- Sofitel Hotel Brisbane Central
Some of the world brightest medical minds came together in the final weekend of March to tackle paediatric brain cancer, sharing insights and research findings to bolster the fight against the insidious childhood disease.
View 2023 Program
| Day 1 | |||||
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08:00 |
Registration Open |
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09:00 |
Welcome to Country Songwoman Maroochy, Turrbal Dippil Opening Lyndsey Rice | CEO of Children's Hospital Foundation |
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09:15-10:30 |
Gliomagenesis and Preclinical Models
Chair: Professor Brandon Wainwright |
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Selective pressures shaping pediatric glioma evolution Kids are not small adults – improving preclinical models to optimise translational paediatric neuro-oncology research |
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10:30-11:00 |
Morning tea with poster viewing |
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11:00-12:20 |
Selected Abstracts Chair: Dr Carolin Offenhauser |
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Development of Clinically Relevant Radiotherapy Methods in Mouse Models of Medulloblastoma for Measuring Survival Benefits and Late Effects of Radiosensitising Drugs Dr Jessica Buck Inhibition of the Polyamine Pathway: A Novel Therapeutic Approach to Treat Aggressive Paediatric Medulloblastoma Tumours Dr Aaminah Khan PI3K is a therapeutically targetable genetic dependency in diffuse midline glioma 3D in vitro Assessment of EphA2 CAR T Cell Efficacy in Paediatric Brain Cancer |
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12:20-13:30 |
Lunch |
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13:30-15:00 |
Immunotherapy Chair: Dr Wayne Nicholls |
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Developing a pipeline for the development of novel CAR T cells for paediatric brain cancer How to target immune ‘cold’ brain cancer by immunotherapy? Selective silencing of point-mutated oncogenes with single-nucleotide precision using CRISPR-Cas13 |
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15:00-15:30 |
Afternoon tea with poster viewing |
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15:30-16:30 |
Clinical Translation Chair: Professor Di Yu |
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Can understanding brain development contribute towards new therapeutic approaches for paediatric high-grade gliomas? The road less travelled…..Integrating research into clinical practice |
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16:45 |
Poster session |
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17:30 |
Close |
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18:30-22:00 |
Conference Dinner,
Ballroom 1, Sofitel Brisbane Central
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| Day 2 | |||||
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08:00 |
Registration Open |
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09:00 |
Opening and Acknowledgement of Country |
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09:15-10:30 |
Trial Design and Big Data
Chair: Professor Bryan Day |
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Accelerating the path to cure through more efficient clinical trial design |
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10:30-11:00 |
Morning tea with poster viewing |
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11:00-12:20 |
Selected Abstracts
Chair: Dr Joseph Yunis |
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Fenretinide: a brain penetrant diffuse intrinsic pontine glioma therapeutic Minimally invasive disease monitoring in high-risk childhood brain cancer Fluorinated Polymer-Iron Oxide Probes for Intranasal Delivery of Therapeutic siRNA and MRI Treatment Monitoring of Medulloblastoma Quality of Life and Family Functioning Soon After Paediatric Brain Tumour Diagnosis |
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12:20-13:30 |
Lunch |
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13:30-15:00 |
Survivorship
Chair: Professor Natalie Bradford |
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Recent advances in improving neuropsychological outcomes for paediatric brain tumour patients – Are we entering a new era? Understanding trends in health service utilisation for children with brain tumours: the highs and lows of navigating linked administrative data Preclinical models of cancer therapy-induced adverse effects |
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15:00-15:30 |
Afternoon tea with poster viewing |
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15:30-16:45 |
Emerging Breakthroughs
Chair: Dr Tim Hassall |
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Lineage-specific dependencies in paediatric-type diffuse high-grade glioma Structure of neurofibromin reveals new insights into neurofibromatosis type 1 (NF1) |
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16:45-17:15 |
Awards and Closing |
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17:30-19:30 |
Conference Networking Function, Soiree Terrace, The Sofitel Brisbane Central |
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