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Some of the worlds brightest medical and scientific minds are coming together in March 2025 to tackle paediatric brain cancer, sharing insights and research findings to bolster the fight against the insidious childhood disease.
Featuring presentations from internationally renowned leaders in the field and chaired by Children’s Brain Cancer Centre Co-Directors Tim Hassall and Brandon Wainwright, the event will provide researchers with the opportunity to network and ideate together.
The conference program time zone is GMT+10, Brisbane, Queensland, Australia.
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18:30 – 21:00 |
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08:00 |
Registration Open – Tea and coffee available |
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09:00 |
Acknowledgement of Country
Conference Opening
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09:10-10:30 |
Plenary Session |
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Session Chair: Prof Brandon Wainwright
Machine learning, new tumour suppressors and targets in childhood brain tumours Prof Richard Gilbertson Development of the Diffuse Midline Glioma ADvanced mAchine-learning Precision Treatment Strategy (DMG-ADAPTS) Prof Matt Dun |
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10:30-11:00 |
Morning tea with poster viewing |
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11:00-12:20 |
Selected Abstracts |
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Session Chair: Prof David Eisenstat
Theranostic Nanoparticle-Mediated Delivery of PLK1 siRNA Slows Medulloblastoma Growth In vivo Ms Jiayuan Zhu Suppressing Recurrence in SHH subgroup Medulloblastoma usng the OLIG1 inhibitor CT-179 Dr Michelle Li CRIPSR screens in serum-free medium reveal conditionally essential genes in Paediatric CNS tumours Ms Yuqing Liang Ex vivo Modelling of Brain Cancer using 3D Bioprinting Mr Philipp Graber |
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12:20-13:30 |
Lunch |
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13:30-15:00 |
Plenary Session |
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Session Chair: Dr Michelle Li
The role of nuclear F-actin and replication stress in cancer cell telomere maintenance Prof Tracy Bryan How the Human Brain can Influence Giloma Therapeutic Sensitivity Prof Cedric Bardy Uncovering novel mechanisms of receptor tyrosine kinase activation in paediatric brain cancers Dr Lauren Brown |
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15:00-15:30 |
Afternoon tea with poster viewing |
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15:30-17:00 |
Selected Abstract Session |
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Session Chair: Prof Greig de Zubicaray Disparities in Quality of Life and Family Functioning 24 months after Diagnosis of a Childhood Brain Tumour Dr Kate Young Trauma-mapping parent experiences of Paediatric brain tumour: A trauma theory framework analysis Ms Melanie Rolfe A novel model of radiotherapy-induced neurotoxic late effects based on fractionated administration. Dr Hana Starobova and Dr Jessica Buck DNA Damage Response Inhibitors Enhance the Efficacy of Radiation in Preclinical Models of Medulloblastoma Dr Meegan Howlett |
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Plenary Session |
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Session Chair: Prof Greig de Zubicaray Age-appropriate models of paediatric brain tumours reveal age-dependent tumour-immune interactions A/Prof Raelene Endersby |
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17:00 |
Close |
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18:30-22:00 |
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08:00 |
Registration Open – Tea and coffee available |
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09:00 |
Opening |
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09:15-10:30 |
Plenary Session |
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Session Chair: Prof David Ziegler Advancing Brain Tumour Care Through International Collaboration: Insights from PNOC Prof Sabine Mueller Reprogramming the brain tumour microenvironment to enhance anti-tumour immunity A/Prof Theo Mantamadiotis |
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10:30-11:00 |
Morning tea with poster viewing |
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11:00-12:20 |
Selected Abstracts
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Session Chair: Dr Marija Kiska Dual targeting of oncogenic cofactors MYC and histone deacetylasae in high-risk childhood brain tumours Dr Satyanarayana Gadde Single-cell Analysis of ONC201 and Paxalisib Resistance Mechanisms in Diffuse Intrinsic Pontine Giloma Dr Clara Savary Mechanistic Insights of ACT001 in DIPG and the Development of Combination Therapies with Mcl-1 Inhibitors Dr David Lorincz CAR T Cell Therapy for Paediatric CNS Tumours: Building a National Framework for Agile Translation Dr Ryan Cross |
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12:20-13:30 |
Lunch |
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13:30-15:00 |
Plenary Session |
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Session Chair: Bryan Day
Computational immunogenomic approaches to predict neoantigens treatment response Dr Nic Waddell Precision medicine in paediatric diffuse high grade gliomas: the next steps to improve outcome? Dr Dong Anh Khuong Quang New Frontiers in Epigenetic Therapeutics and Real-time liquid Biopsy based tracking: towards enhancing immunotherapy Prof Sudha Rao |
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15:00-15:30 |
Afternoon tea with poster viewing |
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15:30-16:45 |
Invited Speaker Session |
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Session Chair: Prof Geraldine O’Neill
The 3D Regulatory Genome in Cancer Dr Joanna Achinger-Kawecka Unveiling Epigenomic Vulnerabilities in Diffuse Midline Glioma: Paving the Way for Innovative Therapeutic Approaches A/Prof Fa Valdes Mora |
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16:45-17:15 |
Awards and Closing |
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