Anthony Mascia is Associate Professor in Departments of Radiation Oncology and Pediatrics, as well as the Director of Medical Physics for the Cincinnati Children’s Hospital and University of Cincinnati Proton Therapy Center. Anthony completed his PhD at the University of California, Los Angeles in the area of proton therapy beam delivery, optimization and detection. He has over 18 years of experience in proton therapy, having participated in or led the opening of four proton therapy center across the United States. His areas of research are radiation detector design and implementation, relative and absolute proton dosimetry, and experimental design and implementation for biological studies. Most recently, in the area of FLASH research and translation, Anthony is Principal Investigator or Co-Investigator on several project, from the absolute dosimetry of FLASH radiation to studying the FLASH effect in animal models. Under his co-direction, Cincinnati Children’s Hospital and University of Cincinnati completed FAST-01, the first in-human clinical trial in proton FLASH radiotherapy. FAST-02, a subsequent proton in-human FLASH clinical trial, is open, with additional clinical trials under development.