Assoc. Professor Andrew Ellisdon

Victorian Cancer Agency Fellow, Monash University

A/Prof Andrew Ellisdon is a Victorian Cancer Agency Fellow and Head of the Structural Biology of Cell Signalling Laboratory at the Monash Biomedicine Discovery Institute. He trained in structural biology as a joint Marie-Curie and EMBO Fellow at the MRC LMB (UK) before establishing his research team at Monash. His research is focused on capturing an atomic resolution view of ‘signalling in action’ by determining the structures of protein complexes formed by GTPase-activating proteins (GAP) and guanine nucleotide exchange factors (GEFs). This resolution is enabled by combining recent advances in cryo-EM with cutting-edge proteomic and artificial intelligence tools. Current research combines cryo-EM with proteomics to uncover the structural basis of Neurofibromin (NF1) dysregulation in disease.